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Properties of HPMC

Mar. 22, 2021

Properties of HPMC

Hydroxypropyl methylcellulose (HPMC) is also known as hypromellose. It is a chemically modified cellulose polymer.

As a powder, HPMC is off-white and is considered safe.

It has a high viscosity and is often used in ophthalmic preparations as an artificial tear for dry eyes.

HPMC can be used for various applications and as a coating agent in the pharmaceutical industry.

However, whenever you need hydroxypropyl methylcellulose, always get the best quality from a trusted manufacturer.

Physical properties of HPMC

1. Density

The actual density is 1.39 g/cm3.

2. Physical properties and appearance

HPMC is an off-white granular fibrous substance.

3. Stability

HPMC is in solid form, flammable, and incompatible with strong oxidants.

4. Solubility

HPMC is almost insoluble in absolute ethanol, acetone and ether. It swells into a slightly cloudy colloidal solution after mixing in cold water.

The chemical properties of HPMC

1. Appearance

HPMC is a powdery off-white substance.

2. Color change temperature

The temperature is between 190°C and 200°C.

3. Carbonization temperature

The carbonization temperature of HPMC is between 280-300°C.

4. Surface tension

A 2% aqueous solution is 42-56dyn/cm.

5. Visual density

The visual density is 0.25 ~ 0.70g/cm (but usually about 0.5g/cm), and the specific gravity is 1.26 ~ 1.31.

6. Particle size

The particle size of special specifications is 40 ~ 60 mesh. The pass rate of 100 mesh is greater than 98.5%, and the pass rate of 80 mesh is 100%.

7. Solubility

HPM is soluble in water and other solvents, such as propanol and ethanol.

The solubility changes with the viscosity, the lower the viscosity, the greater the solubility, and vice versa.

The HPMC aqueous solution has surface activity. However, different specifications of HPMC have different gelling temperatures, which have high transparency and stable performance.

The decrease in methoxy content also leads to a decrease in HPMC, which leads to an increase in gel point, a decrease in surface activity, and a decrease in water solubility.

Other properties of HPMC


Dimensional stability

Water retention

Salt-tolerant low ash powder

pH stability

Excellent film forming ability

Thickening ability

Extensive enzyme resistance

It is an off-white powdery substance with various physical and chemical properties.

Hydroxypropyl methylcellulose can be used in different industries and can also be used as a substitute for gluten and gelatin in vegetarian-friendly products.

Finally, always cooperate with trusted manufacturers for the best deal of hydroxypropyl methylcellulose.

We are hydroxypropyl methylcellulose manufacturers. If you are interested in our products, please feel free to contact us.


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